Dosage ; 80mg OD
Combinations ; - see below
1. Valsartan / Hydrochlorthiazide
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Diovan | Novartis Pharma | C.Mehta & Co Ltd. | 80mg | 28 | Capsule | per capsule | KES 3,644.00 |
| Diovan | Novartis Pharma | C.Mehta & Co Ltd. | 160mg | 28 | Capsule | per capsule | KES 4,289.00 |
| Valsartan More info | |
|---|---|
| Mode Of Action | It blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in a number of tissues. It does not cause persistent dry cough that normally complicates ACE inhibitors therapy. This is due to the fact that it does not inhibit the breakdown of kinins. |
| Drug Indication | Mild to moderate hypertension |
| Precautions | Severe CHF; active peptic ulcer |
| Contra-Indications | Pregnancy and breastfeeding; billiary obstruction; renal impairment, allergy to the drug. |
| Side Effects | Symptomatic hypotension, hyperkaleamia and disturbances of liver function, angioedema, taste disturbances, dizziness |
| Dosage | 80mg OD |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Angiotensin (AT1 ) receptor blockers |
| 1. Valsartan / Hydrochlorthiazide | |
|---|---|
| Mode Of Action | It blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in a number of tissues. It does not cause persistent dry cough that normally complicates ACE inhibitors therapy. This is due to the fact that it does not inhibit the breakdown of kinins. it also has anti-diuretic activity |
| Drug Indication | Hypertension |
| Precautions | See under Valsartan and Hydrochlorthiazide |
| Contra-Indications | See under Valsartan and Hydrochlorthiazide |
| Side Effects | See under Valsartan and Hydrochlorthiazide |
| Dosage | 1 Once Daily |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTI NG ON THE CARDIO-VASCULAR SYSTEM |
| Drug Sub-Category | Angiotensin (AT1 ) receptor blockers |
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| Co-diovan | Novartis Pharma | C.Mehta & Co Ltd. | 80mg/12.5mg | 28 | Capsule | per capsule | KES 2,909.00 |
| Co-diovan | Novartis Pharma | C.Mehta & Co Ltd. | 160mg / 12.5mg | 28 | Capsule | per capsule | KES 3,423.00 |
| Valzaar H | Torrent Pharmaceuticals Ltd. | Medox Pharmaceuticals Ltd. | 80mg/12.5mg | 30 | Capsule | per capsule | KES 790.00 |
| Valzaar H | Torrent Pharmaceuticals Ltd. | Medox Pharmaceuticals Ltd. | 160mg / 12.5mg | 30 | Capsule | per capsule | KES 1,190.000 |